In the context of the EU-ToxRisk project we require fast and affordable high throughput transcriptomics analysis. The EU-ToxRisk project is a European flagship project that aims to establish strategies for chemical safety testing that are based on non-animal approaches and aims to integrate mechanistic information into new test methods. This project involves 39 partners from academia, SME and larger industries. The project also collaborates extensively with the U.S. NIEHS/National Toxicology Program and the U.S. Environmental Protection Agency. The ultimate aim of the project is to provide a new safety assessment strategy for risk assessment, with the aim to provide protection of the human population for chemical exposure.